Table 2.
Gene | dbSNP | Genotype Frequencies a | Allelic Frequencies a | p b | |||
---|---|---|---|---|---|---|---|
OPRM1 | rs1799971 | AA | AG | GG | A | G | |
Lebanese patients n = 96 (Current study) | 76 (79.2) | 18 (18.8) | 2 (2.1) | 0.89 | 0.11 | – | |
European HapMap n = 113 | 80 (70.8) | 31 (27.4) | 2 (1.8) | 0.84 | 0.16 | 0.336 | |
Japanese HapMap n = 86 | 29 (33.7) | 34 (39.5) | 23 (26.7) | 0.53 | 0.47 | 0.0001 * | |
Chinese HapMap n = 43 | 18 (41.9) | 19 (44.2) | 6 (14) | 0.64 | 0.36 | 0.0001 * | |
Sub-Saharan African HapMap n = 60 | 60 (100) | 0 (0) | 0 (0) | 1 | 0 | 0.0008 * | |
ABCB1 | rs1045642 | CC | CT | TT | C | T | |
Lebanese patients n = 96 (Current study) | 34 (35.4) | 38 (39.6) | 24 (25) | 0.55 | 0.44 | – | |
European HapMap n = 113 | 17 (15) | 63 (55.8) | 33 (29.2) | 0.43 | 0.57 | 0.0025 * | |
Japanese HapMap n = 86 | 22 (25.6) | 49 (57) | 15 (17.4) | 0.54 | 0.46 | 0.063 | |
Chinese HapMap n = 42 | 16 (38.1) | 17 (40.5) | 9 (21.4) | 0.58 | 0.42 | 0.895 | |
Sub-Saharan African HapMap n = 113 | 89 (78.8) | 23 (20.4) | 1 (0.8) | 0.89 | 0.11 | 0.0001 * |