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. 2015 Mar 19;16(3):6298–6311. doi: 10.3390/ijms16036298

Table 2.

Genotype and allele frequencies of OPRM1 and ABCB1 variants in our population. Comparison with previously published data.

Gene dbSNP Genotype Frequencies a Allelic Frequencies a p b
OPRM1 rs1799971 AA AG GG A G
Lebanese patients n = 96 (Current study) 76 (79.2) 18 (18.8) 2 (2.1) 0.89 0.11
European HapMap n = 113 80 (70.8) 31 (27.4) 2 (1.8) 0.84 0.16 0.336
Japanese HapMap n = 86 29 (33.7) 34 (39.5) 23 (26.7) 0.53 0.47 0.0001 *
Chinese HapMap n = 43 18 (41.9) 19 (44.2) 6 (14) 0.64 0.36 0.0001 *
Sub-Saharan African HapMap n = 60 60 (100) 0 (0) 0 (0) 1 0 0.0008 *
ABCB1 rs1045642 CC CT TT C T
Lebanese patients n = 96 (Current study) 34 (35.4) 38 (39.6) 24 (25) 0.55 0.44
European HapMap n = 113 17 (15) 63 (55.8) 33 (29.2) 0.43 0.57 0.0025 *
Japanese HapMap n = 86 22 (25.6) 49 (57) 15 (17.4) 0.54 0.46 0.063
Chinese HapMap n = 42 16 (38.1) 17 (40.5) 9 (21.4) 0.58 0.42 0.895
Sub-Saharan African HapMap n = 113 89 (78.8) 23 (20.4) 1 (0.8) 0.89 0.11 0.0001 *

a Value represents the number of patients with percentage shown in parenthesis; b p values are obtained using χ2 test between the number of patients of each genotype compared to our study [19,20]; * Statistically significant result.