Table 4.
Bivariate and multivariate cox proportional hazards model of incident TB among HIV infected individuals on pre-ART follow-up in, JUSH, 2013, N = 584
| Variables | Category | Crude hazard ratio (95% CI) | ¥ Adjusted hazard ratio (95% CI) |
|---|---|---|---|
| Age group (years) | 15-29 | 1.00 | |
| 30-39 | 0.88 (0.48 1.62) | ||
| 39+ | 0.38 (0.15 0.98)* | ||
| Sex (N = 587) | Female | 1.00 | |
| Male | 0.61 (0.35 1.06) | ||
| Marital status | Never married | 1.00 | |
| Married | 0.56 (0.28 1.12) | ||
| Separated | 0.83 (0.29 2.35) | ||
| Divorced | 0.72 (0.27 1.91) | ||
| Widowed | 0.23 (0.05 1.02) | ||
| Level of education (N = 585) | Primary | 1.00 | |
| No education | 1.85 (0.95 3.63) | ||
| Secondary | 1.38 (0.67 2.85) | ||
| Tertiary | 0.63 (0.15 2.74) | ||
| People per household (N = 583) | <=2 | 1.00 | |
| >2 | 1.54 (0.76 3.09) | ||
| Tobacco use | Yes | 1.00 | |
| No | 0.66 (0.35 1.25) | ||
| Alcohol use | Yes | 1.00 | |
| No | 0.68 (0.37 1.23) | ||
| Past opportunistic infection (N = 587) | No | 1.00 | 1.00 |
| Yes | 2.57 (1.43 4.61)** | 2.41 (1.33 4.34) | |
| WHO clinical stage | Stage I/ II | 1.00 | 1.00 |
| Stage III/ IV | 3.39 (1.90 6.02)** | 3.05 (1.61 5.81)** | |
| Functional status | Working | 1.00 | |
| Ambulatory | 1.29 (0.58 2.88) | ||
| Bedridden | 5.65 (0.77 41.32) | ||
| IPT prophylaxis® | Yes | 1.00 | 1.00 |
| No | 1.95 (1.02 3.74) | 2.02 (1.04 3.92)* | |
| CD 4 + cells count (cells/μl) (N = 585) | > = 500 | 1.00 | 1.00 |
| 350 – 499 | 3.06 (1.47 6.37)** | 2.87 (1.37 6.03)** | |
| <350 | 2.34 (1.02 5.39)* | 3.16 (1.04 3.92)** |
*Statistically significant at p ≤ 0.05 **statistically significant at p ≤ 0.01.
®Exchanging the reference at adjusted level of analysis results in (aHR = 0.5).
¥Global test of proportional-hazards assumption for predictors fitted to Cox proportional hazard model was not significant (df = 5, ch2 = 7.04, p = 0.218).