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. Author manuscript; available in PMC: 2016 Apr 28.
Published in final edited form as: J Control Release. 2015 Feb 25;204:30–37. doi: 10.1016/j.jconrel.2015.02.031

Figure 6.

Figure 6

Protection against malarial challenge. Mice were immunized with three doses of RAS each with 2,000 sporozoites at an interval of two weeks. All animals were challenged by IV injection of 200 live P. yoelii sporozoites 7 days after the final immunization. Parasitemia were monitored at indicated days post-challenge by blood smear (A) and blood parasite burdens were determined by RT-qPCR on day 10 post challenge (B). The results are expressed as Mean ± SD. n=8, **p<0.01 and ***p<0.001 between ID and Laser+ID group in A or ***p<0.001 and ns, not significant in B.