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. Author manuscript; available in PMC: 2015 Apr 13.
Published in final edited form as: J Nat Sci. 2015 Apr;1(4):e71.

Figure 1. Schematic presentation of embryonic cardiac developmental stages, growth and formation of four chambered heart.

Figure 1

A. Formation of primary heart crescent at ~E7.5. B. Development of heart tube at ~E8.5 from the cardiac crescent cells. C. Formation of primitive atria and ventricles at ~E9.5 by looping of heart tube. D. Heart chamber formation at ~E10.5 from primitive chambers. E (i) Defective cardiac development leads to embryonic heart failure and in-utero death by cardiac arrest at ~E14.5. E (ii) Formation of the four-chambered heart at ~E14.5. The successive developmental stages during mouse embryogenesis are shown in top panel with representative pictures. Abbreviations: HF, Heart Fields; CM, Cardiogenic Mesoderm; AP, Arterial Pole; OT, Outflow Tract; HT, Heart Tube; VP, Venous Pole; RV, Right Ventricle; LV, Left Ventricle; RA, Right Atrium; LA, Left Atrium; PA, Pulmonary Artery; A; Aorta.