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. Author manuscript; available in PMC: 2015 Apr 13.
Published in final edited form as: Amyloid. 2010 Nov 10;17(0):118–128. doi: 10.3109/13506129.2010.530008

Figure 2.

Figure 2

Thioflavin T assay for h-IAPP in the presence and absence of curcumin. h-IAPP was incubated with curcumin at 0 μM (black line), 10 μM (red line) and 50 μM (blue line) during fibril formation. A: Representative spectra for the given curcumin concentrations. B: Fluorescence intensity quantification (n = 6). Six separate measurements yielded a highly reproducible curcumin dependent loss in signal intensity. This is evidenced by the standard deviation for the final plateau values after 16 h, which were 0.02 and 0.01 (arbitrary units; equivalent to 2 and 1% of the control amplitude without curcumin) for 10 and 50 μM curcumin, respectively.