Table 4.
Survival comparisons of 1999–2002 versus 1995–1998 when adjusted by variables individually using Cox Model (N = 3517).
| Variable | Size | OS |
CSS |
||||||
|---|---|---|---|---|---|---|---|---|---|
| Estimate | SE | p-value | Hazard ratio (95% CI) | Estimate | SE | p-value | Hazard ratio (95% CI) | ||
| Race (ref = white) | 2495 | ||||||||
| Non-white | 1022 | 0.015 | 0.048 | 0.757 | 1.015 (0.924,1.116) | −0.032 | 0.054 | 0.551 | 0.968 (0.872,1.076) |
| Year 1999–2002 (ref = 1995–1998) | −0.215 | 0.045 | <0.001 | 0.807 (0.739,0.881) | −0.242 | 0.049 | <0.001 | 0.785 (0.713,0.864) | |
| Marital status (ref = married) | 2058 | ||||||||
| Unmarried | 1459 | 0.225 | 0.045 | <0.001 | 1.252 (1.146,1.368) | 0.139 | 0.049 | 0.005 | 1.150 (1.044,1.266) |
| Year 1999–2002 (ref = 1995–1998) | −0.218 | 0.045 | <0.001 | 0.804 (0.737,0.877) | −0.244 | 0.049 | <0.001 | 0.783 (0.712,0.862) | |
| Figo stage (ref = IB2) | 446 | ||||||||
| II | 1732 | 0.359 | 0.082 | <0.001 | 1.432 (1.219,1.683) | 0.373 | 0.093 | <0.001 | 1.452 (1.210,1.742) |
| III + IVA | 1339 | 1.147 | 0.081 | <0.001 | 3.150 (2.684, 3.697) | 1.210 | 0.091 | <0.001 | 3.352 (2.800, 4.014) |
| Year 1999–2002 (ref = 1995–1998) | −0.234 | 0.045 | <0.001 | 0.791 (0.725,0.864) | −0.262 | 0.049 | <0.001 | 0.769 (0.699,0.846) | |
| Histology (ref = squamous cell carcinoma) | 2785 | ||||||||
| Adenocarcinoma | 354 | 0.103 | 0.072 | 0.151 | 1.109 (0.963,1.276) | 0.164 | 0.077 | 0.035 | 1.178 (1.012,1.371) |
| Other/unknown | 378 | 0.238 | 0.069 | 0.0005 | 1.268 (1.109,1.451) | 0.294 | 0.074 | <0.001 | 1.342 (1.160,1.552) |
| Year 1999–2002 (ref = 1995–1998) | −0.216 | 0.045 | <0.001 | 0.806 (0.739,0.880) | −0.244 | 0.049 | <0.001 | 0.784 (0.713,0.863) | |
| Lymph node status (ref = LN−) | 1817 | ||||||||
| Distant LN+ | 271 | 0.861 | 0.076 | <0.001 | 2.366 (2.039,2.747) | 0.991 | 0.081 | <0.001 | 2.696 (2.300,3.160) |
| Regional LN+ | 529 | 0.250 | 0.066 | <0.001 | 1.284 (1.129,1.460) | 0.390 | 0.070 | <0.001 | 1.477 (1.287,1.696) |
| Other/unknown | 900 | 0.520 | 0.052 | <0.001 | 1.683 (1.520,1.863) | 0.543 | 0.058 | <0.001 | 1.721 (1.536,1.929) |
| Year 1999–2002 (ref = 1995–1998) | −0.196 | 0.045 | <0.001 | 0.822 (0.753,0.897) | −0.226 | 0.049 | <0.001 | 0.798 (0.725,0.878) | |
| Surgery extent (ref = no surgery/incisional biopsy/unknown) | 2254 | ||||||||
| Local ablation or excision | 248 | −0.411 | 0.092 | <0.001 | 0.663 (0.553,0.794) | −0.443 | 0.104 | <0.001 | 0.642 (0.524,0.788) |
| Hysterectomy/exenteration/other surgery | 1015 | −0.558 | 0.053 | <0.001 | 0.572 (0.516,0.634) | −0.498 | 0.057 | <0.001 | 0.607 (0.543,0.679) |
| Year 1999–2002 (ref = 1995–1998) | −0.230 | 0.045 | <0.001 | 0.794 (0.728,0.867) | −0.256 | 0.049 | <0.001 | 0.774 (0.703,0.852) | |
| Radiation type (ref = combined EBRT + brachytherapy | 2114 | ||||||||
| EBRT/brachytherapy/other | 1403 | 0.351 | 0.044 | <0.001 | 1.421 (1.303,1.550) | 0.376 | 0.049 | <0.001 | 1.457 (1.324,1.603) |
| Year 1999–2002 (ref = 1995–1998) | −0.225 | 0.045 | <0.001 | 0.799 (0.732,0.872) | −0.252 | 0.049 | <0.001 | 0.777 (0.706,0.855) | |
Red color used to highlight statistically significant p-values.