Table 5.

Best fitting Multivariable Cox model for overall survival (N = 3517, AIC = 31399).

Variable	Size	Parameter estimate	SE	p-value	Hazard ratio (95% CI)
Year 1999–2002 [ref =1995–1998 (n=1758)]	1759	−0.250	0.045	<0.001	0.779 (0.713,0.850)
Age [ref = <41 (n = 732)]
41–55	1413	−0.079	0.064	0.219	0.924 (0.815,1.048)
>55	1372	0.221	0.063	<0.001	1.247 (1.102,1.411)
Marital status [ref = married (n = 2058)]
Unmarried	1459	0.100	0.046	0.029	1.106 (1.010,1.210)
FIGO stage [ref = IB2 (n = 446)]
II	1732	0.207	0.086	0.015	1.230 (1.040,1.455)
III + IVA	1339	0.834	0.088	<0.001	2.301 (1.938, 2.734)
Histology [ref = squamous cell carcinoma (n = 2785)]
Adenocarcinoma	354	0.234	0.072	0.001	1.263 (1.096,1.456)
Other/unknown	378	0.308	0.069	<0.001	1.360 (1.187,1.558)
Lymph node status [ref = LN− (n = 1817)]
Distant LN+	271	0.628	0.078	<0.001	1.874 (1.608, 2.184)
Regional LN+	529	0.271	0.068	<0.001	1.311 (1.146, 1.499)
Other/unknown	900	0.282	0.053	<0.001	1.326 (1.194,1.472)
Surgery Extent [ref = no surgery/incisional biopsy/unknown (n = 2254)]
Local ablation or excision	248	−0.311	0.093	<0.001	0.733 (0.611,0.879)
Hysterectomy/exenteration/other surgery	1015	−0.482	0.060	<0.001	0.618 (0.549,0.694)
Radiation type [ref = combined EBRT + brachytherapy (n = 2114)]
EBRT/brachytherapy/other	1403	0.409	0.046	<0.001	1.505 (1.375,1.646)

Red color used to highlight statistically significant p-values.