Table 6.
Best-fitting Multivariable Cox model for cause specific survival (N = 3517, AIC = 25951).
Variable | Size | Parameter estimate | SE | p-value | Hazard ratio (95% CI) |
---|---|---|---|---|---|
Year 1999–2002 [ref = 1995–1998 (n=1758)] | 1759 | −0.274 | 0.049 | <0.001 | 0.760 (0.690,0.837) |
FIGO stage [ref = IB2 (n = 446)] | |||||
II | 1732 | 0.314 | 0.096 | 0.001 | 1.369 (1.135,1.652) |
III + IVA | 1339 | 0.995 | 0.097 | <0.001 | 2.706 (2.236, 3.275) |
Histology [ref = squamous cell carcinoma (n = 2785)] | |||||
Adenocarcinoma | 354 | 0.318 | 0.078 | <0.001 | 1.374 (1.179,1.601) |
Other/unknown | 378 | 0.352 | 0.075 | <0.001 | 1.422 (1.227,1.647) |
Lymph node status [ref = LN− (n = 1817)] | |||||
Distant LN+ | 271 | 0.730 | 0.083 | <0.001 | 2.075 (1.763, 2.444) |
Regional LN+ | 529 | 0.384 | 0.073 | <0.001 | 1.468 (1.272, 1.694) |
Other/unknown | 900 | 0.314 | 0.060 | <0.001 | 1.369 (1.218,1.538) |
Surgery Extent [ref = no surgery/incisional biopsy/unknown (n = 2254)] | |||||
Local Ablation or excision | 248 | −0.365 | 0.104 | 0.0005 | 0.694 (0.565,0.852) |
Hysterectomy/exenteration/other surgery | 1015 | −0.465 | 0.064 | <0.001 | 0.628 (0.553,0.714) |
Radiation type [ref = combined EBRT + brachytherapy (n = 2114)] | |||||
EBRT/brachytherapy/other | 1403 | 0.422 | 0.050 | <0.001 | 1.525 (1.382,1.684) |
Red color used to highlight statistically significant p-values.