Table 2. Association analysis of blood pressure and inflammatory markers, all patients.
| A) Correlation analysis – coefficients of correlation shown | ||||||
|---|---|---|---|---|---|---|
| MPO | Elastase | Leukocyte count | Granulocyte count | Interleukin-6 | Systolic/diastolic BP | |
| BP systolic | 0.089 (n.s.) | 0.293** | 0.245** | −0.111 (n.s.) | 0.155 (n.s.) | 0.611** |
| BP diastolic | 0.179* | 0.402** | 0.076 (n.s.) | −0.153 (n.s.) | −0.026 (n.s.) | 0.611** |
| BP mean | 0.167 (p = 0.06) | 0.393** | 0.172* | −0.156 (n.s) | 0.019 (n.s) | 0.866**/0.931** |
| CRP | ||||||
| BP systolic | −0.068 (n.s.) | |||||
| BP diastolic | −0.034 (n.s.) | |||||
| BP mean | −0.053 (n.s) | |||||
| B) Multivariate analysis | ||
|---|---|---|
| Parameter | Significance | Partial eta-square |
| Elastase | <0.001 | 0.141 |
| Leukocyte count | <0.01 | 0.080 |
| MPO | n.s | |
Correlation analysis (A) of systolic, diastolic and mean blood pressure with markers of neutrophil activation and inflammation (MPO, elastase, leukocyte count, granulocytic count, Interleukin-6, CRP). Coefficients of correlation are shown. Correlations were calculated using a Pearson product-moment correlation coefficient if variables were interval-scaled and normally distributed (MPO, elastase, leukocyte count, granulocytic count, Interleukin-6). Otherwise, rank correlation using Spearman's coefficient was performed (CRP).
Significant correlations were included into a multivariate linear model including systolic, diastolic and mean blood pressure as dependent variables (B).
* = p ≤ 0.05, ** = p ≤ 0.01. BP systolic = systolic blood pressure, BP diastolic = diastolic blood pressure, BP mean = mean arterial blood pressure, MPO = Myeloperoxidase, CRP = C-reactive protein.