. 2015 Apr 10;59(5):2540–2547. doi: 10.1128/AAC.04067-14

TABLE 2.

In vitro drug susceptibility of the Dd2^attB (parental), Dd2^attB::WT-pfap2-mu, and Dd2^attB::160Asn-pfap2-mu transfectant strains to dihydroartemisinin using a 6-h pulse assay

Strain	IC₅₀ (nM) (95% CI)^a
Strain	Modified 48-h assay	6-h pulse assay
Dd2^attB (parental)	4.1 (3.7–4.6)	10.8 (8.6–13.5)
Dd2^attB::WT-pfap2-mu	3.9 (3.8–4.1)	8.8 (8.1–9.4)
Dd2^attB::160Asn-pfap2-mu	3.9 (3.6–4.2)	9.1 (6.3–13.1)

The dihydroartemisinin susceptibility of each parasite line was assessed in both assays by two independent experiments, with two replicates for each experiment.