FIG 3.

(A) Schematic representation of genomic rearrangement due to mobilization of the type F resistance element. Black pentagons indicate IS26s and their orientations. hmgB, fumarylacetoacetate hydrolase gene. Alignments of the complete nucleotide sequence of the cloned fragment from PA058447 and genome sequences of PAO1 and UCBPP-PA14 are shown. The gray bar indicates the type F resistance element. (B) Structural comparison of PA058447 type F resistance element (IS26 transposon), NCGM2.S1 resistance element (IS26 transposon), and Tn21. Color shading indicates homologous regions. Coding sequences are shown as pentagons (green, IS26; blue, transposon; yellow, integron; red, antibiotic resistance gene; gray, other function or hypothetical protein).