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Simulated human fT > MIC profile for cefepime at 2 g q8h in humans compared to that observed in mice
| MIC (mg/liter) | Cefepime fT > MIC (%) |
|
|---|---|---|
| Human | Mousea | |
| 4 | 100 | 100 |
| 8 | 84 | 83 |
| 16 | 61 | 65 |
| 32 | 39 | 38 |
| 64 | 16 | 20 |
| 128 | 1 | 1 |
This profile is similar in mice irrespective of AAI101 administration.
