TABLE 3.
Virus titers in organs of infected ferretsa
| Virus (type) | Day | Virus titer of ferrets infected in: |
||
|---|---|---|---|---|
| Nasal turbinates | Trachea | Lung | ||
| A/Sapporo/114/2013 (H275Y mutant) | 3 | 6.0 ± 1.6 | 4.1 | 2.0 |
| 6 | 2.2, 5.0 | 2.5 | —b | |
| A/Shizuoka-c/99/2013 (wild type) | 3 | 6.7 ± 0.9 | 2.7, 3.4 | 3.2 ± 0.3 |
| 6 | 2.0 ± 0.2 | — | — | |
Ferrets were intranasally infected with 0.5 ml of 106 PFU virus. Three ferrets from each group were euthanized on days 3 and 6 postinfection for viral titration. Virus replication in the liver, duodenum, spleen, and kidneys was also examined; no virus was detected in these organs. The values are presented as the mean log10 PFU ± SD/g or as individual titers when virus was not recovered from all three ferrets.
—, virus not detected.