TABLE 3.
Interactions of two L. sericata peptides against E. coli and M. luteus
| Peptide combination | sumFIC (n)a | Interaction |
|---|---|---|
| E. coli | ||
| PCecL5 + Stomox1 | 0.98 ± 0.25 (9) | Additive |
| Cec6 + PCecL4 | 0.82 ± 0.17 (11) | Additive |
| PCecL3 + Cec2 | 0.82 ± 0.22 (2) | Additive |
| PCecL5 + Cec6 | 0.85 ± 0.14 (2) | Additive |
| Cec2 + Stomox2 | 0.64 ± 0.04 (3) | Additive |
| Cec6 + Cec5 | 0.60 ± 0.17 (3) | Additive |
| PCecL4 + PCecL2 | 0.72 ± 0.10 (3) | Additive |
| M. luteus | ||
| PCecL4 + Cec3 | 1.00 ± 0.00 (3) | Additive |
| PCecL4 + Def4 | 0.85 ± 0.17 (4) | Additive |
| Stomox1 + Def6 | 1.00 ± 0.00 (3) | Additive |
| Cec6 + Def4 | 0.41 ± 0.13 (15) | Synergistic |
| Cec4 + Def3 | 0.60 ± 0.00 (3) | Additive |
a
Values are means ± standard deviations from several experiments. The number of experiments is given in parentheses. The sumFIC results are interpreted as follows: a sumFIC of ≤0.5 indicates synergy, a sumFIC of >0.5 and ≤1 indicates additive effects, and a sumFIC of <2 indicates antagonism.