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. 2015 Apr 10;59(5):2588–2595. doi: 10.1128/AAC.04476-14

TABLE 3.

Comparison of geometric mean MICs according to anatomic site of infection

Antimicrobial and MIC type Geometric mean MIC (μg/ml)a
Ratio of geometric mean MICs (95% CI)
Pharyngeal (n = 205) Rectal (n = 261) Urethral (n = 976) Pharyngeal vs urethral Rectal vs urethral Rectal vs pharyngeal
Azithromycin
    Geometric mean MIC 0.3129 0.3034 0.3035 1.03 (0.90–1.19) 1.00 (0.87–1.15) 0.97 (0.81–1.16)
    City-adjusted geometric mean MIC 0.3369 0.3166 0.2954 1.14 (0.98–1.33) 1.07 (0.94–1.23) 0.94 (0.78–1.12)
Cefixime
    Geometric mean MIC 0.0270 0.0325 0.0292 0.92 (0.82–1.04) 1.11 (0.98–1.26) 1.20 (1.03–1.40)b
    City-adjusted geometric mean MIC 0.0275 0.0323 0.0287 0.96 (0.85–1.09) 1.13 (0.99–1.28) 1.17 (1.01–1.37)b
Ceftriaxone
    Geometric mean MIC 0.0155 0.0161 0.0154 1.00 (0.88–1.14) 1.05 (0.93–1.18) 1.04 (0.89–1.22)
    City-adjusted geometric mean MIC 0.0153 0.0157 0.0150 1.02 (0.90–1.17) 1.05 (0.93–1.19) 1.03 (0.88–1.20)
Ciprofloxacin
    Geometric mean MIC 0.1241 0.1759 0.1160 1.07 (0.62–1.84) 1.52 (0.92–2.51) 1.41 (0.73–2.77)
    City-adjusted geometric mean MIC 0.1053 0.1599 0.1132 0.93 (0.54–1.60) 1.41 (0.85–2.34) 1.52 (0.78–2.95)
Penicillin
    Geometric mean MIC 0.6229 0.7080 0.7911 0.79 (0.67–0.93)b 0.90 (0.76–1.05) 1.14 (0.93–1.39)
    City-adjusted geometric mean MIC 0.6660 0.7492 0.7813 0.85 (0.72–1.00) 0.96 (0.82–1.12) 1.13 (0.93–1.37)
Tetracycline
    Geometric mean MIC 1.2974 1.5214 1.5367 0.84 (0.71–1.01) 0.99 (0.83–1.18) 1.17 (0.94–1.46)
    City-adjusted geometric mean MIC 1.3684 1.5763 1.5187 0.90 (0.75–1.08) 1.04 (0.87–1.24) 1.15 (0.93–1.43)
a

Geometric mean MICs, ratios of geometric mean MICs, and 95% confidence intervals (CIs) were calculated by employing generalized linear models.

b

P < 0.05 (CI does not contain 1).