TABLE 3.
Comparison of geometric mean MICs according to anatomic site of infection
Antimicrobial and MIC type | Geometric mean MIC (μg/ml)a |
Ratio of geometric mean MICs (95% CI) |
||||
---|---|---|---|---|---|---|
Pharyngeal (n = 205) | Rectal (n = 261) | Urethral (n = 976) | Pharyngeal vs urethral | Rectal vs urethral | Rectal vs pharyngeal | |
Azithromycin | ||||||
Geometric mean MIC | 0.3129 | 0.3034 | 0.3035 | 1.03 (0.90–1.19) | 1.00 (0.87–1.15) | 0.97 (0.81–1.16) |
City-adjusted geometric mean MIC | 0.3369 | 0.3166 | 0.2954 | 1.14 (0.98–1.33) | 1.07 (0.94–1.23) | 0.94 (0.78–1.12) |
Cefixime | ||||||
Geometric mean MIC | 0.0270 | 0.0325 | 0.0292 | 0.92 (0.82–1.04) | 1.11 (0.98–1.26) | 1.20 (1.03–1.40)b |
City-adjusted geometric mean MIC | 0.0275 | 0.0323 | 0.0287 | 0.96 (0.85–1.09) | 1.13 (0.99–1.28) | 1.17 (1.01–1.37)b |
Ceftriaxone | ||||||
Geometric mean MIC | 0.0155 | 0.0161 | 0.0154 | 1.00 (0.88–1.14) | 1.05 (0.93–1.18) | 1.04 (0.89–1.22) |
City-adjusted geometric mean MIC | 0.0153 | 0.0157 | 0.0150 | 1.02 (0.90–1.17) | 1.05 (0.93–1.19) | 1.03 (0.88–1.20) |
Ciprofloxacin | ||||||
Geometric mean MIC | 0.1241 | 0.1759 | 0.1160 | 1.07 (0.62–1.84) | 1.52 (0.92–2.51) | 1.41 (0.73–2.77) |
City-adjusted geometric mean MIC | 0.1053 | 0.1599 | 0.1132 | 0.93 (0.54–1.60) | 1.41 (0.85–2.34) | 1.52 (0.78–2.95) |
Penicillin | ||||||
Geometric mean MIC | 0.6229 | 0.7080 | 0.7911 | 0.79 (0.67–0.93)b | 0.90 (0.76–1.05) | 1.14 (0.93–1.39) |
City-adjusted geometric mean MIC | 0.6660 | 0.7492 | 0.7813 | 0.85 (0.72–1.00) | 0.96 (0.82–1.12) | 1.13 (0.93–1.37) |
Tetracycline | ||||||
Geometric mean MIC | 1.2974 | 1.5214 | 1.5367 | 0.84 (0.71–1.01) | 0.99 (0.83–1.18) | 1.17 (0.94–1.46) |
City-adjusted geometric mean MIC | 1.3684 | 1.5763 | 1.5187 | 0.90 (0.75–1.08) | 1.04 (0.87–1.24) | 1.15 (0.93–1.43) |
Geometric mean MICs, ratios of geometric mean MICs, and 95% confidence intervals (CIs) were calculated by employing generalized linear models.
P < 0.05 (CI does not contain 1).