TABLE 6.
MICs of drugs for mecA-positive passaged mutant strains cured of plasmid and parental strains transduced with plasmids from passaged strains in the USA300 strain SF8300 background
| Strain | MIC (μg/ml) ofa: |
||||||
|---|---|---|---|---|---|---|---|
| NAF | AMP | CFZ | CXT | CTX | CPT | BPR | |
| SF8300 | 32 | 128 | 32 | 64 | 128 | 1 | 1 |
| SF8300ex | 0.5 | <0.25 | 1 | 4 | 4 | <0.25 | 0.5 |
| SF8300ex(pAW8) | <0.25 | <0.25 | 0.5 | 4 | 4 | <0.25 | 0.5 |
| SF8300ex(pYK20) | 32 | 8 | 32 | 32 | 256 | 0.5 | 1 |
| SF8300ex(pYK20COLB*) | 32 | 16 | 64 | 64 | 128 | 32 | 32 |
| SF8300pT(pYK208300T*) | 128 | 16 | 128 | 128 | 256 | 4 | 4 |
| SF8300pT, plasmid cured | 0.5 | 1 | 1 | 4 | 8 | 2 | 1 |
a
NAF, nafcillin; AMP, ampicillin; CFZ, cefazolin; CXT, cefoxitin; CTX, ceftriaxone; CPT, ceftaroline; BRP, ceftobiprole.