TABLE 3.
Parasite loads in infected macrophages during various treatments
| Treatment | No. of amastigotes/100 macrophagesa |
|---|---|
| Infected | 356.3 ± 29.8 |
| Infected + GRA | 79.1 ± 8.5 |
| Infected + GRA | |
| WT TAK1 | 88.0 ± 9.1 AB |
| DN TAK1 | 238.3 ± 26.5 A |
| DN TAK1 + SB203580 | 324.7 ± 33.9 B |
| WT MyD88 | 64.3 ± 7.2 C |
| DN MyD88 | 193.0 ± 18.0 C |
| WT IRAK1 | 56.7 ± 4.9 D |
| DN IRAK1 | 186.3 ± 19.5 D |
| WT TRAF6 | 83.1 ± 9.9 E |
| DN TRAF6 | 241.1 ± 23.8 E |
| Scrambled TLR2 siRNA | 78.3 ± 8.1 F |
| TLR2 siRNA | 219.0 ± 22.3 F |
| Scrambled TLR4 siRNA | 86.3 ± 9.2 G |
| TLR4 siRNA | 231.3 ± 23.5 G |
a
Values are means ± SD; n = 3. Letters indicate combinations whose values were significantly different by Student's t test at P < 0.001.