FIG. 2.

Schematic demonstrates in vivo experimental design. Scaffolds are prepared, stacked, and coated with collagen before implantation into the left knee of model rodents. Replicates are designed such that four animals will be assessed for biological function at weeks 2, 6, and 12 postimplantation, and an additional six will undergo biomechanical testing (BMT) at week 12.