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Cell expansion. (A) Cumulative fold increase of cell number over three passages, measured following plating NT or p21sh cells into passage 2. Data from n=6 total combined from two independent cell preparations. Asterisk indicates p<0.05 compared to NT. (B) Percentage of cells in S phase as measured by propidium iodide cell cycle analysis. Undifferentiated iPSCs and primary mouse chondrocytes served as controls. Data from n=3 and groups not sharing a letter indicate p<0.05.
