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. 2015 Apr 8;7(6):422–427. doi: 10.14740/jocmr2117w

Table 2. Published Reports of VPR.

Author (year) Case report or series (n) Dose of VPR Concomitant therapies Comments
Pasic et al [20] (1993) Report 2 g loading with 100 mg q6h and 100 mg PRN watery stool No Colitis resolution; death from sepsis on POD 52
Shetler et al [21] (2001) Series (7) 250 mL of premixed solution (1 g vancomycin in 1 L sterile H2O) q6h Yes (all IV metronidazole, 5/7 oral vancomycin) Colitis resolution in four of the seven patients
Nathanson et al [22] (2001) Report 500 mg in 500 mL saline BID Yes (IV metronidazole for 10/10 days) Colitis resolution with discharge to home
Apisarnthanarak et al [23] (2002) Series (9) Variable (0.5 - 1 g q4 - q12h) Yes (all IV/oral metronidazole, 7/9 oral vancomycin) Resolution in 89%
Kim et al [24] (2013) Series (47) 1 g q6h Yes (oral vancomycin and IV) Resolution without surgery in 70%