Pasic et al [20] (1993) |
Report |
2 g loading with 100 mg q6h and 100 mg PRN watery stool |
No |
Colitis resolution; death from sepsis on POD 52 |
Shetler et al [21] (2001) |
Series (7) |
250 mL of premixed solution (1 g vancomycin in 1 L sterile H2O) q6h |
Yes (all IV metronidazole, 5/7 oral vancomycin) |
Colitis resolution in four of the seven patients |
Nathanson et al [22] (2001) |
Report |
500 mg in 500 mL saline BID |
Yes (IV metronidazole for 10/10 days) |
Colitis resolution with discharge to home |
Apisarnthanarak et al [23] (2002) |
Series (9) |
Variable (0.5 - 1 g q4 - q12h) |
Yes (all IV/oral metronidazole, 7/9 oral vancomycin) |
Resolution in 89% |
Kim et al [24] (2013) |
Series (47) |
1 g q6h |
Yes (oral vancomycin and IV) |
Resolution without surgery in 70% |