Table 4. Changes in Variables After 6-Month Sitagliptin Monotherapy (n = 5).
| Subjects studied (n) | Pre-treatment | Post-treatment | P value | |
|---|---|---|---|---|
| Body weight (kg) | 3 | 64.6 (3.6) | 61.1 (2.5) | 0.087 |
| Systolic blood pressure (mm Hg) | 4 | 126 (12) | 133 (17) | 0.568 |
| Diastolic blood pressure (mm Hg) | 4 | 75 (4) | 83 (10) | 0.345 |
| Plasma glucose (mg/dL) | 5 | 192 (76) | 107 (22) | 0.060 |
| HbA1c (%) | 5 | 7.0 (0.3) | 5.9 (0.7) | 0.036 |
| LDL-cholesterol (mg/dL) | 2 | 135 (4) | 116 (18) | 0.465 |
| Triglyceride (mg/dL) | 4 | 131 (44) | 128 (36) | 0.957 |
| HDL-cholesterol (mg/dL) | 3 | 59 (16) | 48 (11) | 0.148 |
| AST (IU/L) | 5 | 30 (16) | 28 (19) | 0.789 |
| ALT (IU/L) | 5 | 30 (17) | 26 (14) | 0.710 |
| γGTP (IU/L) | 3 | 39 (11) | 35 (24) | 0.789 |
| eGFR (mL/min/1.73 m2) | 5 | 111 (36) | 108 (40) | 0.486 |