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. 2015 Apr 8;7(6):490–494. doi: 10.14740/jocmr2133w

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Copyright 2015, O’Grady et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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(a) Scattered, angulated and rounded, atrophic fibers (H&E, cryostat section). (b) Large numbers of necrotic and basophilic regenerating fibers (H&E, paraffin section). (c) Necrotic fibers occurring singly and in small groups, many showing myophagocytosis (H&E, cryostat section). (d) Small numbers of CD8⁺ T lymphocytes, mostly confined to perivascular locations (CD8 immunohistochemistry). (e) Macrophages within necrotic fibers (CD68 immunohistochemistry). (f) Patchy sarcolemmal upregulation of MHC class I antigen (MHC class I immunohistochemistry).