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. Author manuscript; available in PMC: 2016 Mar 28.
Published in final edited form as: J Control Release. 2015 Jan 28;202:40–48. doi: 10.1016/j.jconrel.2015.01.031

Table 2.

Pharmacokinetic parameters for CPA-LLP

Parameter Mean ± standard deviation
Cmax (%ID/g) 4.05 ± 0.38
AUCLast (%ID∙ h/g) 131.6 ± 35.3
AUC0-∞ (%ID∙ h/g) 147.0 ± 36.0
Terminal elimination half-life (h) 9.94 ± 3.4
Systemic clearance (g/h) 0.7089 ± 0.141
Vz (g) 9.96 + 3.4
Mean residence time (h) 58.0 ± 6.3

Cmax, predicted maximum blood concentration; AUCLast, area under the blood concentration curve from zero to the last sampling point; AUC0-∞, area under the blood concentration curve from zero to infinity; Vz, apparent volume of distribution in the terminal phase.