Table 3. Scoring and distribution (%) of mild and advanced glomerular lesions in the groups under study.
Mild Lesions | 0 Absent | 1 <25% | 2 25–50% | 3 >50% | Total Score | |
Thickening of Bowman´s Capsule | Sham, n (%) | 7 (100%) | 0 | 0 | 0 | 0.00±0.00 |
CRF, n (%) | 1 (14.3%) | 3 (42.9%) | 1 (14.3%) | 2 (28.6%) | 1.57±0.43** | |
Hyalinosis of the vascular pole | Sham, n (%) | 7 (100%) | 0 | 0 (0%) | 0 (0%) | 0.00±0.00 |
CRF, n (%) | 1 (14.3%) | 6 (85.7%) | 0 | 0 | 0.86±0.14** | |
Glomerular atrophy | Sham, n (%) | 7 (100%) | 0 | 0 | 0 | 0.00±0.00 |
CRF, n (%) | 1 (14,3%) | 6 (85.7%) | 0 | 0 | 0.86±0.14** | |
Hypercellularity | Sham, n (%) | 7 (100%) | 0 | 0 | 0 | 0.00±0.00 |
CRF, n (%) | 0 | 7 (100%) | 0 | 0 | 1.00±0.00** | |
Dilatation of the Bowman’s Space | Sham, n (%) | 7 (100%) | 0 | 0 | 0 | 0.00±0.00 |
CRF, n (%) | 5 (71.4%) | 2 (28.6%) | 0 | 0 | 0.29±0.18 | |
Total Group Score | Sham | 0.00±0.00 | ||||
CRF | 0.91±0.12*** | |||||
Advanced lesions | None of the previous (0) | Thickening of GBM(1) | Mesangial expansion(2) | Nodular sclerosis(3) | Global Glomerulosclerosis (4) | Total Score |
Sham, n (%) | 7 (100%) | 0 | 0 | 0 | 0 | 0.00±0.00 |
CRF, n (%) | 0 | 1 (14.3%) | 5 (71.4%) | 1 (14.3%) | 0 | 2.0±0.22** |
Results are presented as mean ± SEM: *- p < 0.05
**- p < 0.01, and
***- p < 0.001 versus Sham group.