Table 4. Scoring and distribuition (%) of mild and advanced tubulointerstitial lesions in the groups under study.

Mild Lesions		0 Absent	1 <25%	2 25–50%	3 >50%	Total Score
Tubular Hyaline Droplets	Sham, n (%)	7 (100%)	0	0	0	0.00±0.00
	CRF, n (%)	0	7 (100%)	0	0	1.00±0.00 **
TBM Irregularity	Sham, n (%)	7 (100%)	0	0	0	0.00±0.00
	CRF, n (%)	0	3 (42.9%)	2 (28.5%)	2 (28.5%)	1.86±0.34**
Tubular Dilatation	Sham, n (%)	7 (100%)	0	0	0	0.00±0.00
	CRF, n (%)	2 (28.5%)	1 (14.3%)	2 (28.5%)	2 (28.5%)	1.57±0.48*
Interstitial Inflammatory Infiltrate	Sham, n (%)	4 (57.2%)	3 (42.9%)	0	0	0.29±0.18
	CRF, n (%)	0	0	7 (100%)	0	2.00±0.00**
Vacuolar Tubular Degeneration	Sham, n (%)	0	7 (100%)	0	0	1.00±0.00
	CRF, n (%)	3 (42.9%)	3 (42.9%)	1 (14.3%)	0	0.71±0.29
Total Group Score	Sham					0.26±0.08
	CRF					1.43±0.15***
Advanced Lesions		0-Absent	1- <25%	2–25–50%	3- >50%	Score
Hyaline cylinders	Sham, n (%)	6 (85.7%)	1 (14.3%)	0	0	0.14±0.14
	CRF, n (%)	0	1 (14.3%)	6 (85.7%)	0	1.86±0.14**
Tubular Calcification	Sham, n (%)	7 (100%)	0	0	0	0.00±0.00
	CRF, n (%)	7 (100%)	0	0	0	0.00±0.00
Necrosis	Sham, n (%)	7 (100%)	0	0	0	0.00±0.00
	CRF, n (%)	2 (28.6%)	5 (71.4%)	0	0	0.71±0.18*
IFTA	Sham, n (%)	7 (100%)	0	0	0	0.00±0.00
	CRF, n (%)	0	3 (42.9%)	4 (57.1%)	0	1.57±0.20**
Total Group Score	Sham					0.04±0.04
	CRF					1.04±0.16***

Results are means ± SEM

*- p < 0.05

**- p < 0.01, and

***- p < 0.001 versus the Sham group.