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. 2015 Apr 13;10(4):e0123152. doi: 10.1371/journal.pone.0123152

Fig 4. TLR-3 deficiency does not ameliorate adipose tissue inflammation.

Fig 4

After 16 weeks of low fat diet (LFD) or high fat diet (HFD) intervention, adipose tissue of wild-type (WT) and TLR-3-/- mice was investigated for inflammatory parameters. (a) Adipose tissue of mice stained for F4/80, magnification 20x, (b) number of crown-like structures in adipose tissue. Inflammatory markers were measured (c) F480, (d) CD68, (e) MCP-1, (f) TNFα, (g) CXCL1. (h) mRNA levels of TLR-3 in WT mice fed a LFD or HFD for 16 weeks. * p<0.05, ** p<0.01. Number of mice per group: WT-LFD n = 10; WT-HFD n = 10; TLR-3-/-LFD n = 7; TLR-3-/-HFD n = 9. Data are shown as means ± SEM.