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. 2015 Apr 13;10(4):e0124582. doi: 10.1371/journal.pone.0124582

Fig 7. Fluorescent microscopy of the nuclear import of ferritin heavy chain 1 after treatment with paraquat.

Fig 7

Knock-down and over-expression in stably transfected NCI-H295R1-TR AAAS knock-down and over-expression cells was induced by 48 h treatment with doxycycline. Scr, scrambled shRNA. KD, knock-down. EV, empty vector (= pcDNA4/TO). OE, over-expression. Native, without paraquat treatment. PQ, paraquat treatment. n, minimum number of analysed cells per cell type. P-values: * P<0.05, *** P<0.001. Significant differences were measured with unpaired Student’s t-Test. Boxplot widths are proportional to the square root of the samples sizes. Whiskers indicate the range outside 1.5 times the inter-quartile range (IQR) above the upper quartile and below the lower quartile. Outliers were plotted as dots. The experiment was repeated twice.