Table 4. Allelic and genotypic frequencies of 8 SNPs of KCNJ10 in the GGEs patients (n = 483) and the healthy controls (n = 284).
| Genotypes | Alleles | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| GGEs patients | Healthy controls | GGEs A:B | |||||||||
| SNPs | Alleles | AA | AB | BB | AA | AB | BB | p-value | Control A:B | OR(95% CI) | p-value |
| rs1053074 | G/T | 58 | 200 | 224 | 44 | 116 | 122 | 0.35 | 316648; 204/360 | 0.86(0.69–1.07) | 0.18 |
| rs1130183 | C/T | 482 | 0 | 1 | 284 | 0 | 0 | 0.44 | 964/2;568/0 | - | 0.28 |
| rs12729701 | A/G | 282 | 160 | 35 | 147 | 111 | 25 | 0.16 | 724/230 ;405/161 | 1.25(0.99–1.58) | 0.06 |
| rs12402969 | C/T | 5 | 59 | 418 | 2 | 40 | 241 | 0.68 | 69/895;44/522 | 0.92(0.62–1.36) | 0.66 |
| rs1186688 | T/C | 42 | 208 | 231 | 34 | 115 | 134 | 0.33 | 292/670;183/383 | 0.91(0.73–1.14) | 0.42 |
| rs1186685 | T/C | 21 | 175 | 285 | 22 | 96 | 166 | 0.14 | 217/745;140/428 | 0.89(0.70–1.14) | 0.35 |
| rs6690889 | T/C | 264 | 193 | 23 | 145 | 111 | 27 | 0.04 | 721/239;401/165 | 1.24(0.98–1.57) | 0.07 |
| rs1890532 | C/G | 299 | 158 | 24 | 182 | 85 | 15 | 0.74 | 756/2065;449/115 | 0.94(0.73–1.21) | 0.64 |
OR, odds ratio; CI, confidence interval; GGEs, genetic generalized epilepsies.