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. 2015 Feb 20;19(4):806–814. doi: 10.1111/jcmm.12497

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© 2015 The Authors. Journal of Cellular and Molecular Medicine published by John Wiley & Sons Ltd and Foundation for Cellular and Molecular Medicine.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Fig 2 — Accumulation of copper in Atp7b^−/− mice as demonstrated by LA-ICP-MS imaging. 30-μm thick cryo-sections from wild-type (left panel) and Atp7b^−/− mice (right panel) at age between 10 and 24 months were subjected to LA-ICP-MS imaging and the content of carbon (C), copper (Cu), zinc (Zn), and iron (Fe) determined. Please note that the content of C that served as reference is given in %, while the total concentrations of Cu, Zn, and Fe are given in μg/g liver tissue.