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Antiproliferative activity of ligand and metal complexes on human leukaemia HL-60 cells at three concentrations
| Compound | Inhibition of cell proliferation (%)* | ||
|---|---|---|---|
| 10 μM | 1 μM | 0.1 μM | |
| HL | 0 | 0 | 0 |
| [Cu(L)(Cl)]·C2H5OH (1) | 98.9 | 41.3 | 2.0 |
| [Cu(L)2]·H2O (2) | 99.9 | 96.0 | 5.0 |
| [Cu(L)(Br)]·H2O (3) | 98.8 | 35.5 | 0 |
| [Cu(L)(NO3)]·2CH3CH2OH (4) | 96.8 | 45.8 | 4.0 |
| [VO2 (L)]·2H2O (5) | 4.0 | 0 | 0 |
| [Ni(L)2]·H2O (6) | 5.7 | 0 | 0 |
| CuCl2·2H2O | 0 | 0 | 0 |
| (VO)SO4·2H2O | 0 | 0 | 0 |
| NiCl2·6H2O | 0 | 0 | 0 |
SEM < ±4% of a single experiment in triplicate.
