Table 2. Expression profiles of cytokines and chemokines in BALF.
| (pg/ml) | control | OVA 6 h | OVA 24 h | OVA 48 h | OVA 72 h | OVA 8 day |
|---|---|---|---|---|---|---|
| IL-4 | 2.1±0.0 | 986.8±212.4* | 71.8±46.4 | 6.5±1.2 | 4.0±0.4 | 2.2±0.0 |
| IL-13 | 0.4±0.1 | 69.2±16.1* | 55.2±19.0* | 50.0±12.2* | 22.6±10.2 | 0.3±0.0 |
| TNF-α | 0.6±0.1 | 9.0±1.2* | 1.4±0.3 | 0.9±0.4 | 0.5±0.1 | 0.4±0.1 |
| IL-6 | 0.3±0.0 | 456.3±139.9* | 21.3±12.5 | 3.7±1.3 | 0.4±0.0 | 0.3±0.0 |
| KC | 20±2.2 | 610.3±87.2* | 307.0±71.9* | 215.8±45.4* | 159.8±27.0 | 107.0±7.9 |
| eotaxin-1 | 0.6±0.2 | 25.1±8.4* | 16.1±4.9 | 21.1±4.3* | 17.6±3.9 | 2.6±0.5 |
| RANTES | 1.7±0.1 | 2.5±0.2* | 2.1±0.1 | 2.4±0.2* | 2.0±0.1 | 1.6±0.1 |
| TGF-β1 | 23.7±3.8 | 257.8±54.6* | 358.7±47.7* | 362.7±37.1* | 338.4±26.2* | 175.7±33.2* |
Cytokines and chemokines in BALF were detected at each time point (6 h, 24 h, 48 h, 72 h, and 8 days after the last OVA challenge).
Data are presented as means ± SEM (n = 5).
*p <0.05 compared with control mice.