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. 2015 Apr 13;10(4):e0123575. doi: 10.1371/journal.pone.0123575

Fig 2. Down-regulation of miR-223 promotes degranulation.

Fig 2

Mast cells were transfected with miR-223 inhibitor (miR-223 inhibitor group) or its control (control group). The cells were then sensitized with anti-2,4-dinitrophenyl (DNP) immunoglobulin E and triggered with (black column) or without (white column) DNP-HSA. After triggering for 1 h, release of β-hexosaminidase were detected in the two groups. Data are represented as the mean ± SD for three experiments (n = 6). *P < 0.05 compared to the control group.