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. 2015 Apr 13;10(4):e0123575. doi: 10.1371/journal.pone.0123575

Fig 4. PI3K-inhibitor (LY294002) decreases degranulation.

Fig 4

The cells were transfected with miR-223 inhibitor or its control and were sensitized with anti-DNP IgE overnight. The cells were then triggered with DNP-HSA with or without LY294002. After triggering for 1 h, release of β-hexosaminidase were detected in four groups. Data are represented as the mean ± SD for three experiments (n = 6). *P < 0.01 compared to the control group; # P < 0.01 compared to the miR-223 inhibitor group.