Table 1. Baseline characteristics of participants in the diabetic and non-diabetic groups.
| Variables | Original population (N = 6532) | Study population (N = 5277) | Non-diabetis (N = 4915) | Diabetis (N = 362) | P-value |
|---|---|---|---|---|---|
| Age, years | 43±17 | 43±16 | 42±15 | 56±14 | <0.001 |
| Male gender (%) | 3137 (48%) | 2471 (46.8%) | 2287 (46.5%) | 184 (50.8%) | 0.11 |
| 1st degree relatives with stroke (%) | 1373 (21%) | 1039 (19.7%) | 924 (18.8%) | 115 (31.8%) | <0.001 |
| Underlying diseases | |||||
| Hypertension (%) | 2374 (36.3%) | 1744 (33%) | 1497 (30.5%) | 247 (68.2%) | <0.001 |
| Dyslipidemia (%) | 3136 (48%) | 2531 (48%) | 2262 (46%) | 269 (74.3%) | <0.001 |
| Hyperuricemia (%) | 1846 (28.3%) | 1430 (26.9%) | 1313 (26.7%) | 107 (29.6%) | 0.24 |
| Medication uses | |||||
| Statins (%) | 250 (3.8%) | 148 (2.8%) | 100 (2%) | 48 (13.3%) | <0.001 |
| Fibrates (%) | 121 (1.9%) | 76 (1.4%) | 42 (0.9%) | 34 (9.4%) | <0.001 |
| Insulin (%) | 49 (0.8%) | 20 (0.4%) | 0 (0%) | 20 (5.5%) | <0.001 |
| Oral hyperglycemic agents (%) | 350 (5.4%) | 216 (4.1%) | 0 (0%) | 216 (59.7%) | <0.001 |
| Anti-hypertensive agents (%) | 1947 (29.8%) | 1364 (25.8%) | 1149 (23.4%) | 215 (59.4%) | <0.001 |
| Anti-platelet agents (%) | 805 (12.3%) | 473 (9%) | 400 (8.1%) | 73 (20.2%) | <0.001 |
| Anti-acid agents (%) | 198 (3%) | 146 (2.8%) | 117 (2.4%) | 29 (8%) | <0.001 |
| Biochemical measures | |||||
| HbA1c, % (mmol/mol) | 5.36 (35)±1.06 | 5.33 (34.6)±1.01 | 5.15 (32.7)±0.54 | 7.72 (60.9)±2.16 | <0.001 |
| Fasting glucose, mmol/L | 5.24±1.59 | 5.2±1.52 | 4.91±0.52 | 9.11±3.67 | <0.001 |
| Total cholesterol, mmol/L | 4.73±0.98 | 4.76±0.97 | 4.71±0.93 | 5.35±1.34 | <0.001 |
| Triglyceride, mmol/L | 1.43±0.95 | 1.42±0.95 | 1.37±0.87 | 2.17±1.5 | <0.001 |
| HDL-C, mmol/L | 1.43±0.39 | 1.44±0.39 | 1.44±0.38 | 1.34±0.5 | <0.001 |
| LDL-C, mmol/L | 2.97±0.71 | 3±7 | 2.97±0.68 | 3.34±0.82 | <0.001 |
| Systolic blood pressure, mm Hg | 116±18 | 115±17.8 | 114±17.4 | 128±19.3 | <0.001 |
| Diastolic blood pressure, mm Hg | 74.9±11.3 | 74.9±11.3 | 74.5±11.2 | 80.1±11.1 | <0.001 |
| Uric acid, μmol/L | 378±107 | 375±106 | 374±105 | 387±121 | <0.01 |
| Creatinine, μmol/L | 80.4±28.3 | 79.6±19.5 | 78.7±17.7 | 84±35.4 | <0.01 |
| Waist circumference, cm | 79.5±11.1 | 79.8±11.4 | 79±10.9 | 87.2±10.8 | <0.001 |
Data were presented as number (%), or mean±standard deviation.