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. 2015 Apr 13;10(4):e0123513. doi: 10.1371/journal.pone.0123513

Table 5. Interaction analysis between rs3128935 genotypes and high-risk population or age.

a) rs3128935 genotypes and high-risk population
Variables Resolver N(%) Chronic N(%) OR (95% CI)
TT genotypes with drug using 102 (41.5) 117 (53.7) 1.00
CT/CC genotypes with drug using 52 (21.1) 25 (11.5) 0.40 (0.24–0.74)
TT genotypes with HD 73 (29.7) 57 (26.1) 0.37 (0.20–0.69)
CT/CC genotypes with HD 19 (7.7) 19 (8.7) 0.48 (0.20–1.11)
P for multiplicative interaction P = 0.013
b) rs3128935 genotypes and age
Variables Resolver N(%) Chronic N(%) OR (95% CI)
TT genotypes with ≥ 40 years 76 (30.8) 75 (34.4) 1.00
CT/CC genotypes with ≥ 40 years 22 (8.9) 24 (11.0) 1.09 (0.55–2.17)
TT genotypes with < 40 years 99 (40.2) 99 (45.4) 0.71 (0.41–1.25)
CT/CC genotypes with < 40 years 49 (20.0) 20 (9.2) 0.30 (0.14–0.61)
P for multiplicative interaction P = 0.035

Logistic regression analyses adjusted for age, gender, high-risk population, and viral genotype.

Abbreviation: HD, hemodialysis.