Table 5. Interaction analysis between rs3128935 genotypes and high-risk population or age.
a) rs3128935 genotypes and high-risk population | |||
Variables | Resolver N(%) | Chronic N(%) | OR (95% CI) |
TT genotypes with drug using | 102 (41.5) | 117 (53.7) | 1.00 |
CT/CC genotypes with drug using | 52 (21.1) | 25 (11.5) | 0.40 (0.24–0.74) |
TT genotypes with HD | 73 (29.7) | 57 (26.1) | 0.37 (0.20–0.69) |
CT/CC genotypes with HD | 19 (7.7) | 19 (8.7) | 0.48 (0.20–1.11) |
P for multiplicative interaction | P = 0.013 | ||
b) rs3128935 genotypes and age | |||
Variables | Resolver N(%) | Chronic N(%) | OR (95% CI) |
TT genotypes with ≥ 40 years | 76 (30.8) | 75 (34.4) | 1.00 |
CT/CC genotypes with ≥ 40 years | 22 (8.9) | 24 (11.0) | 1.09 (0.55–2.17) |
TT genotypes with < 40 years | 99 (40.2) | 99 (45.4) | 0.71 (0.41–1.25) |
CT/CC genotypes with < 40 years | 49 (20.0) | 20 (9.2) | 0.30 (0.14–0.61) |
P for multiplicative interaction | P = 0.035 |
Logistic regression analyses adjusted for age, gender, high-risk population, and viral genotype.
Abbreviation: HD, hemodialysis.