Table 2. Results of the logistic regression differentiating high-grade from low-grade gliomas.

		AUC HGG/LGG [a.u.]	p HGG/LGG
rCBV	enhancing tumor	0.776	0.015*
	edema	0.565	0.376
	enhancing tumor & edema	0.718	0.034*
rCTH	enhancing tumor	0.775	0.014*
	edema	0.811	0.003*
	enhancing tumor & edema	0.807	0.006*
COV	enhancing tumor	0.739	0.029*
	edema	0.650	0.219
	enhancing tumor & edema	0.693	0.070
rCBV & rCTH	enhancing tumor	0.840	0.028* (rCBV), 0.023* (rCTH)
rCBV & rCTH	enhancing tumor & edema	0.876	0.027* (rCBV), 0.006* (rCTH)
rCBV & rCTH & COV	enhancing tumor	0.856	0.076 (rCBV), 0.038* (rCTH), 0.437 (COV)
rCBV & rCTH & COV	enhancing tumor & edema	0.875	0.032* (rCBV), 0.010* (rCTH), 0.358 (COV)

The area under the curve (AUC) as an accuracy measure for discrimination between high-grade and low-grade gliomas. The AUC is calculated for the three parameters and their combinations in the enhancing tumor, the peri-focal edema, and a combined region of enhancing tumor & peri-focal edema. A p-value ≦ 0.05 (marked with *) allows the conclusion that the predictor has enough strength to distinguish between the two groups.