Table 1. MiRNAs differentially expressed between the early and late postpartum breast cancer groups.
miRNA ID | Log2 Fold Change | Log2 mean Expression | Adjusted p-value | Chromosomes |
---|---|---|---|---|
miRNAs overexpressed in early group (≤ 5.2 years postpartum) | ||||
hsa-miR-138 | 2.331 | 13.837 | 0.0046 | Chr 3, 16 |
hsa-miR-660 | 1.137 | 15.849 | 0.0264 | Chr X |
hsa-miR-31 | 1.333 | 18.447 | 0.0264 | Chr 9 |
hsa-miR-135b | 2.813 | 15.552 | 0.0264 | Chr 1 |
hsa-miR-500a | 0.999 | 13.462 | 0.0264 | Chr X |
hsa-miR-19b | 0.672 | 22.512 | 0.0264 | Chr 13, X |
hsa-miR-17 | 1.085 | 15.314 | 0.0264 | Chr 13 |
hsa-miR-362-3p | 0.948 | 5.668 | 0.0335 | Chr X |
hsa-miR-106a | 0.874 | 21.138 | 0.0389 | Chr X |
hsa-miR-454 | 1.378 | 8.447 | 0.0395 | Chr 17 |
hsa-miR-502-5p | 0.816 | 14.491 | 0.0417 | Chr X |
hsa-miR-934 | 2.621 | 12.172 | 0.0477 | Chr X |
miRNAs underexpressed in early group (≤ 5.2 years postpartum) | ||||
hsa-miR-892a | -2.671 | 8.959 | 0.0264 | Chr X |
hsa-miR-199a-5p | -1.236 | 21.199 | 0.0264 | Chr 1, 19 |
hsa-miR-542-5p | -1.082 | 14.069 | 0.0264 | Chr X |
Differentially expressed miRNAs. MiRNAs differentially expressed between the two postpartum interval groups identified. Fifty six samples were processed, with early group (≤ 5.2 years postpartum), representing 12 samples, and late group (≥ 5.3 years postpartum), representing 44 samples. MiRNAs identified based on their expression from a quantitative RT-PCR. The listed miRNAs are ordered based on their adjusted p-values. The last column (Chromosomes) indicates on which chromosomes miRNAs are encoded.