Table 2. Probabilities and QALY losses for each single sequela used in the model.

Parameter	Base case	Distribution	References
Proportion of sequelae
Skin necrosis (%)	1.50	Uniform (1.20; 1.80)	[87]
Amputation with substantial disability (%)	1.00	Uniform (0.80; 1.20)	[88]
Hearing loss with cochlear implantation (%)	2.00	Uniform (1.60; 2.40)	[88]
Moderately severe bilateral hearing loss (%)	5.00	Uniform (4.00; 6.00)	[88]
Any unilateral or bilateral hearing loss (%)	6.00	Uniform (4.80; 7.20)	[88]
Severe neurological disability (%)	2.10	Uniform (1.68; 2.52)	[89]
Mental retard (cognitive problem) (%)	23.70	Uniform (18.96; 28.44)	[87]
Arthritis (%)	2.90	Uniform (2.32; 3.48)	[87]
Epilepsy or seizure (%)	2.00	Uniform (1.60; 2.40)	[88]
Depression (%)	5.70	Uniform (4.56; 6.84)	[87]
Anxiety (%)	7.10	Uniform (5.68; 8.52)	[87]
Blindness (%)	0.40	Uniform (0.32; 0.48)	[88]
Motor deficit (%)	1.90	Uniform (1.52; 2.28)	[2]
Severe speech communication problems (%)	3.80	Uniform (3.04; 4.56)	[88]
Migraine (%)	10.00	Uniform (8.00; 12.00)	[87]
Renal failure (%)	1.90	Uniform (1.52; 2.28)	[87]
QALY losses for survivors with sequelae
Skin necrosis	0.10	Uniform (0.08; 0.12)	[90]
Amputation with substantial disability	0.39	Uniform (0.31; 0.47)	[89]
Hearing loss with cochlear implantation	0.19	Uniform (0.15; 0.23)	[84]
Moderately severe bilateral hearing loss	0.09	Uniform (0.07; 0.11)	[84]
Any unilateral or bilateral hearing loss	0.28	Uniform (0.22; 0.34)	[84]
Severe neurological disability	0.94	Uniform (0.75; 1.13)	[89]
Mental retard (cognitive problem)	0.46	Uniform (0.37; 0.55)	[91]
Arthritis	0.31	Uniform (0.25; 0.37)	[92]
Epilepsy or seizure	0.17	Uniform (0.14; 0.20)	[84]
Depression	0.27	Uniform (0.22; 0.32)	[93]
Anxiety	0.31	Uniform (0.25; 0.37)	[93]
Blindness	0.74	Uniform (0.59; 0.89)	[94]
Motor deficit	0.17	Uniform (0.14; 0.20)	[95]
Severe speech communication problems	0.61	Uniform (0.49; 0.73)	[96]
Migraine	0.19	Uniform (0.15; 0.23)	[97]
Renal failure	0.18	Uniform (0.14; 0.22)	[98]