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. 2015 Apr 13;10(4):e0123757. doi: 10.1371/journal.pone.0123757

Table 1. Baseline characteristics of the whole sample and per group with and without agoraphobia.

All No agoraphobia Agoraphobia p value
(n = 2890) (n = 2766, 95.7%) (n = 124, 4.3%)
Duration between somatic and psychiatric evaluations at baseline, years 1.3±0.5 (0.2–5.7) 1.3±0.5 (0.2–5.7) 1.3±0.4 (0.6–4.3) 0.326
Length of follow-up a , years 5.5±0.4 (4.7–8.5) 5.5±0.4 (4.7–8.5) 5.5±0.4 (5.1–8.2) 0.414
Age, years 49.7±8.8 (35.0–66.6) 49.6±8.8 (35.0–66.6) 50.6±8.4 (35.7–65.9) 0.227
Socioeconomic status b 3.4±1.3 (1.0–5.0) 3.5±1.3 (1.0–5.0) 3.2±1.3 (1.0–5.0) 0.040*
Hypertension c 0.990
No 2309 (79.8%) 2207 (79.8%) 99 (79.8%)
Yes 584 (20.2%) 559 (20.2%) 25 (20.2%)
Body mass index 0.205
Underweight (BMI<18.5 kg/m2) 49 (1.7%) 44 (1.6%) 5 (4.0%)
Normal (18.5 kg/m2≤BMI<25 kg/m2) 1504 (52.0%) 1440 (52.1%) 64 (51.6%)
Overweight (25 kg/m2≤BMI<30 kg/m2) 1002 (34.7%) 959 (34.7%) 43 (34.7%)
Obesity (BMI≥30 kg/m2) 335 (11.6%) 323 (11.7%) 12 (9.7%)
Glucose, fasting state mmol/L 5.5±1.0 (0.3–21.2) 5.5±1.0 (0.3–21.2) 5.5±1.1 (4.2–13.8) 0.598
Total cholesterol/HDL-cholesterol ratio 3.6±1.1 (1.4–12.0) 3.6±1.1 (1.4–12.0) 3.5±1.1 (1.8–7.7) 0.574
Smoking status 0.040*
Never 1140 (39.5%) 1102 (39.8%) 38 (30.7%)
Former/Current 1750 (60.5%) 1664 (60.2%) 86 (69.3%)
Alcohol consumption 0.032*
Nondrinkers 713 (24.7%) 674 (24.4%) 39 (31.5%)
Low (1–6 drinks/week) 1118 (38.7%) 1068 (38.6%) 50 (40.3%)
Moderate (7–13 drinks /week) 594 (20.6%) 568 (20.5%) 26 (21.0%)
High (14+ drinks /week) 465 (16.1%) 456 (16.5%) 9 (7.3%)
Leisure physical activity d 0.265
No 1281 (44.3%) 1220 (44.1%) 61 (49.2%)
Yes 1609 (55.7%) 1546 (55.9%) 63 (50.8%)
Major depressive disorder <0.001**
No 1630 (56.4%) 1581 (57.2%) 49 (39.5%)
Yes 1260 (43.6%) 1185 (42.8%) 75 (60.5%)
Other anxiety disorders e <0.001**
No 2297 (79.5%) 2239 (80.9%) 58 (46.8%)
Yes 593 (20.5%) 527 (19.1%) 66 (53.2%)
Drug dependence f 0.334
No 2812 (97.3%) 2693 (97.4%) 119 (96.0%)
Yes 77 (2.3%) 72 (2.6%) 5 (4.0%)

Data are given as mean ± standard deviation (range) or percentage value.

Statistical analyses used Mann-Whitney-U or Pearson’s chi-square test (* p < 0.05, ** p < 0.001).

SES, socioeconomic status; HDL, high-density lipoprotein; BMI, Body mass index.

a Duration between somatic evaluation at baseline and somatic evaluation at follow-up.

b A value of “3” represents an SES of III (middle class) on the Hollingshead Scale.

c Systolic blood pressure ≥ 140 mmHg and/or diastolic blood pressure ≥ 90 mmHg.

d Physically active at least or more than 20 minutes twice a week.

e Generalized anxiety disorder, panic disorder, posttraumatic stress disorder, and/or social phobia.

f Marijuana, cocaine, solvent, hallucinogen, stimulant, sedative or/and narcotic dependence.