Table 6. Out of range and frequency of adverse events in the Kisumu Adolescent cohort obtained from comparison with values from locally-established reference intervals and DAIDS values.

							Out of range comparison
		This Study		Local reference [15]			MGH-USA [9]			2004 DAIDS [17]
Parameter	Gender	95% reference interval	n	95% reference interval	n	%	95% reference interval	n	%	Cut-off	N	%
Hemoglobin (g/dL)	Female	7.5–14.8	132	8.1–14.2	7	5.3	12–16	37	28.0	>10.9	18	13.6
	Male	11.1–16.7	110	10.6–15.6	1	0.9	13.5–17.5	36	32.7	>10.9	2	1.8
Hematocrit (%)	Female	24.2–43.7	132	24.8–43.1	2	1.5	36–46	30	22.7
	Male	33.7–49.7	110	29.3–48.1	2	1.8	41–53	41	37.3
MCV (%)	Female	59.3–93.2	132	57–91	6	4.5	80–100	76	57.6
	Male	67.4–93.6	110	62–92	1	0.9	80–100	48	43.6
WBC (x109/L)	Female	3.6–9.5	132	3.9–10.2	3	2.3	4.5–11.0	12	9.1	>2.5	3	2.3
	Male	3.6–9.1	110	3.3–8.3	0	0	4.5–11.0	27	24.5	>2.5	0	0
RBC (x1012/L)	Female	3.7–6.0	132	3.3–5.4	1	0.8	4.0–5.2	4	3.0
	Male	4.3–6.4	110	4.1–5.8	2	1.8	4.2–6.3	2	1.8
Lymphocytes (x10 9 /L)	Female	1.2–3.9	132	1.1–3.1	4	3.0	1.0–4.8	2	1.5
	Male	1.4–3.4	110	1.0–4.2	0	0	1.0–4.8	0	0
Neutrophiles (x10 9 /L)	Female	1.3–5.8	132	1.1–3.1	3	2.3	1.8–7.7	20	15.2	>1.3	3	2.3
	Male	0.9–6.7	110	0.8–5.0	0	0	1.8–7.7	27	24.5	>1.3	9	8.2
PLT (x10 9 /L)	Female	126–448	132	134–439	2	1.5	150–350	6	4.5	≥125	3	2.3
	Male	112–474	110	103–386	1	0.9	150–350	14	12.7	≥125	8	7.3
Eosinophils (10 3 cells/μl)	Female	0.04–1.2	132	0–2.2	1	0.8	0–0.5	24	18.2
	Male	0.04–1.6	110	0–1.8	0	0	0–0.5	22	20.0
ALT (μ/L)	Female	5.7–32.5	132	0–65.3	1	0.8	0–35	3	2.3	<76.6	0	0
	Male	7.8–33.9	110	0–42.4	1	0.9	0–35	2	1.8	<100.8	0	0
BUN (mmol/L)	Female	1.2–4.2	132	1.2–4.8	4	3.0	3.6–7.1	116	87.9
	Male	1.2–4.5	110	1.7–4.1	16	14.5	3.6–7.1	96	87.3
Creatinine (μmol/L)	Female	40–69	132	0–87.6	0	0	0–133	0	0	<106.5	0	0
	Male	39–89	110	0–103.7	0	0	0–133	0	0	<151.6	0	0