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. 2015 Apr 13;10(4):e0123829. doi: 10.1371/journal.pone.0123829

Table 2. Cellular functions significantly altered by Cfl2 deficiency.

Cellular Function Subpathway p-value
Cellular Growth and Proliferation Proliferation of cells 1.14 E-22
Proliferation of muscle cells 1.67 E-09
Cytostasis 2.37 E-06
Colony formation of cells 1.74 E-05
Colony formation 3.09 E-05
Formation of cells 3.42 E-05
Arrest in growth of cells 3.89 E-05
Cell Death and Survival Apoptosis 2.73 E-19
Cell death 1.15 E-18
Necrosis 6.79 E-18
Cell death of muscle cells 4.08 E-07
Necrosis of muscle 4.63 E-07
Cell viability 9.66 E-07
Cell survival 1.01 E-06
Cell Cycle Cell cycle progression 6.46 E-17
Mitosis 9.04 E-15
Checkpoint control 4.18 E-13
Segregation of chromosomes 1.59 E-12
Arrest in mitosis 3.69 E-12
M phase 4.41 E-12
Ploidy 2.42 E-10
Ploidy of cells 1.64 E-09
Interphase 1.67 E-09
Cytokinesis 8.97 E-08
G2 phase 3.13 E-07
Senescence of cells 4.82 E-07
DNA recombination 9.85 E-07
G2/M phase transition 1.52 E-06
G1/S phase 1.86 E-06
Polyploidization 2.16 E-06
Length of mitotic spindle 4.50 E-06
Polyploidy of cells 5.15 E-06
Polyploidization of cells 9.06 E-06
Delay in mitosis 1.03 E-05
Arrest in G2 phase 1.14 E-05
S phase checkpoint control 1.21 E-05
S phase 1.41 E-05
Arrest in cell cycle progression 2.02 E-05
Arrest in interphase 2.48 E-05
Delay in initiation of interphase 3.09 E-05
Exit from mitosis 3.97 E-05
Segregation of sister chromatids 3.97 E-05
Formation of mitotic spindle 4.10 E-05
Delay in initiation of M phase 4.71 E-05
G1 phase 6.49 E-05
Homologous recombination 9.30 E-05
DNA damage checkpoint 9.40 E-05
Recombination of cells 9.40 E-05
DNA Replication, Recombination and Repair Checkpoint control 4.18 E-13
Segregation of chromosomes 1.59 E-12
Synthesis of DNA 1.65 E-12
Alignment of chromosomes 2.28 E-09
Repair of DNA 1.07 E-08
Morphology of mitotic spindle 2.58 E-08
DNA damage 1.43 E-07
Metabolism of DNA 1.57 E-07
DNA recombination 9.85 E-07
DNA replication 1.99 E-06
Condensation of chromosomes 2.16 E-06
Recombination 5.46 E-06
Chromosal congression of chromosomes 6.10 E-06
Abnormal morphology of mitotic spindle 1.10 E-05
Quantity of mitotic spindle 1.10 E-05
S phase checkpoint control 1.21 E-05
Damage of chromosomes 1.41 E-05
Homologous recombination repair of DNA 1.59 E-05
Breakage of chromosomes 2.12 E-05
Segregation of sister chromatids 3.97 E-05
Double-stranded DNA break repair 4.08 E-05
Formation of mitotic spindle 4.10 E-05
Formation of nuclear foci 7.26 E-05
Homologous recombination 9.30 E-05
DNA damage checkpoint 9.40 E-05
Recombination of cells 9.40 E-05
Cellular Assembly and Organization Segregation of chromosomes 1.59 E-12
Alignment of chromosomes 2.28 E-09
Missegregation of chromosomes 1.17 E-06
Organization of cytoskeleton 3.61 E-06
Attachment of spindle fibers 6.10 E-06
Chromosomal congression of chromosomes 6.10 E-06
Organization of cytoplasm 8.27 E-06
Quantity of mitotic spindle 1.10 E-05
Polymerization of filaments 1.57 E-05
Polymerization of microtubules 2.54 E-05
Segregation of sister chromatids 3.97 E-05
Formation of mitotic spindle 4.10 E -05
Quantity of chromosome components 6.75 E-05
Formation of nuclear foci 7.26 E-05