Table 3. Biomarker Analysis.
| n | Complete Cohort | eGFR >90 ml per min per 1.73m2 | eGFR ≤90 ml per min per 1.73m2 | TKV ≤1000 cm3 | TKV >1000 cm3 | |
|---|---|---|---|---|---|---|
| Osmolality—mosmol per kg H2O | 139 | 364 (257 to 533) | 377 (266 to 534) | 360 (243 to 506) | 330 (236 to 497) | 417 (332 to 547) |
| NGAL— μg per gcreatinine | 132 | 9.8 (5.3 to 23.7) | 8.7 (4.7 to 22.8) | 11.3 (5.8 to 24.3) | 12.5 (5.3 to 24.3) | 9.0 (5.3 to 21.3) |
| KIM-1—ng per gcreatinine | 132 | 274.6 (131.3 to 457.3) | 272.0 (113.9 to 448.8) | 274.6 (161.3 to 479.9) | 211.6 (106.4 to 362.5) | 391.3 (196.1 to 581.0)* |
| UMOD—mg per gcreatinine | 132 | 16.3 (10.2 to 26.7) | 18.1 (10.9 to 29.8) | 14.8 (9.1 to 25.6) | 19.4 (10.7 to 28.5) | 13.6 (8.3 to 21.6) |
| UACR—mg per gcreatinine | 132 | 14.0 (8.4 to 23.1) | 11.6 (6.9 to 21.8) | 15.4 (9.9 to 27.2) | 12.0 (7.7 to 21.3) | 15.2 (10.4 to 31.1) |
| CC16 – μg per l per gcreatinine | 132 | 2.8 (2.0 to 6.2) | 3.0 (2.0 to 5.9) | 2.6 (2.0 to 6.2) | 2.6 (2.0 to 4.8) | 3.2 (1.7 to 8.9) |
Abbreviations: NGAL—Neutrophil Gelatinase Associated Lipocalin, KIM-1—Kidney Injury Molecule-1, UMOD—Uromodulin, UACR—Urinary Albumin-to-Creatinine Ratio, CC16—Clara Cell Protein 16. Values are reported as median (interquartile range)
* p < 0.05