Table 4. Mutation spectrum for M. smegmatis strains.
| Mutation | Msm (wt) | Δarr | Δfpg | Δfpgarr | ΔudgB | ΔudgB Δarr |
|---|---|---|---|---|---|---|
| C to T or G to A | 30/58 (52%) | 37/57 (64.9%) | 12/38 (31%) | 18/50 (36%) | 22/48 (45.8%) | 21/51 (41.17%) |
| C to A or G to T | NONE | NONE | 3/38 (8%) | 8/50 (16%) | NONE | 2/51 (3.9%) |
| A to G or T to C | 20/58 (34%) | 17/57 (29.8%) | 15/38 (39%) | 10/50 (20%) | 22/48 (45.8%) | 20/51 (39.2%) |
| A to C or T to G | 1/58 (2%) | NONE | 1/38 (3%) | NONE | 3/48 (6.2%) | 3/51 (5.8%) |
| G to C or C to G | 4/58 (7%) | NONE | 6/38 (16%) | 2/50 (4%) | 1/48 (2%) | 5/51 (9.8%) |
| A to T or T to A | 3/58 (5%) | 3/57 (5.2%) | 1/38 (3%) | 9/50 (18%) | NONE | NONE |
| Del 10 | NONE | NONE | NONE | 3/50 (6%) | NONE | NONE |
| No mutation | 21/79 | 17/74 | 29/67 | 10/60 | 19/67 | 13/64 |
Note to Table 4: Mutation spectrum data for Msm (wt), MsmΔudgB::hyg (ΔudgB) were from our earlier studies [20, 27] and those for MsmΔarr::kan (Δarr), MsmΔudgB::hyg Δarr::kan (ΔudgBΔarr), MsmΔfpg::hyg Δarr::kan (ΔfpgΔarr), MsmΔfpg::hyg (Δfpg) were carried out in the present study. Numbers shown in X/Y format indicate that there were X numbers of occurrences within Y numbers of RRDR sequences. Numbers shown as % are the percent occurrences of specific mutations within the RRDR locus that showed mutations.