Fig 2. Decline in cognitive function by baseline cognitive/physical impairment status.

Significantly steeper decline in global cognitive performance (measured with CDR-SB score) was noted in the CI and CPI groups, although physical impairment does not add much above what is seen in the CI group. In contrast, the PI group appears to decline in physical functionality at similar rates with the NI. Results are from the full model adjusted for age, gender, education, race and baseline physical performance.