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. 2015 Apr 13;10(4):e0122878. doi: 10.1371/journal.pone.0122878

Table 2. Rate of decline in physical performance by baseline impairment status.

Model 1 Model 2 Model 3
Slope P value Slope P value Slope P value
Intercept 30.32 <0.001 46.70 <0.001 10.40 <0.001
Overall decline -0.76 <0.001 -0.50 <0.001 -0.70 <0.001
Baseline impairment
NI Ref Ref Ref
PI -7.25 <0.001 -5.59 <0.001 0.04 0.912
CI -1.07 0.036 -1.16 0.021 -0.58 0.138
CPI -8.42 <0.001 -6.92 <0.001 -0.71 0.102
Baseline impairment*Time
NI * Time Ref Ref Ref
PI * Time -0.29 0.164 -0.28 0.158 -0.25 0.294
CI * Time -1.03 <0.001 -0.98 <0.001 -1.22 <0.001
CPI * Time -1.09 <0.001 -1.04 <0.001 -1.17 <0.001

Notes: baseline impairment status is based on baseline PPT score (score of <28 being used as indication of physical impairment). NI = not impaired, PI = physically impaired but cognitively normal, CI = cognitively impaired but physically normal; CPI = cognitively and physically impaired; Performance on the PPT (score) was also used to measure decline in physical function; Model 1 = unadjusted; Model 2 = Model 1 + age + gender + education + race; Model 3 = Model 2 + baseline total PPT score; Rates of decline in physical performance were higher in the CI and CPI groups than in the NI (reference) group. No significant differences were observed in the PI group compared with the NI group.