Table 2. Correlation Table of Cerebral Capillary Permeability with markers of Vitamin D-Calcium-Parathyroid hormone homeostasis.
Animals | Intervention | Region of Interest | Vitamin D | Total Calcium | Ionised Calcium | Parathyroid Hormone | Phosphate |
---|---|---|---|---|---|---|---|
Rats | Vitamin D 6 weeks | CTX | 0.887** | 0.063 | 0.613** | -0.62** | 0.163 |
HPF | 0.803** | 0.253 | 0.679** | -0.68* | 0.005 | ||
Vitamin D 12 weeks | CTX | 0.851** | 0.619** | 0.775** | -0.61** | -0.172 | |
HPF | 0.666** | 0.529** | 0.567** | -0.543** | -0.213 | ||
Vitamin D 24 weeks | CTX | 0.728** | -0.337 | 0.448 | -0.662** | -0.106 | |
HPF | 0.534* | -0.174 | 0.363 | -0.349 | -0.173 | ||
Mice | Vitamin D 6 weeks | CTX | 0.300 | 0.172 | 0.145 | - | -0.164 |
HPF | -0.191 | -0.127 | -0.116 | - | 0.002 | ||
Vitamin D 12 weeks | CTX | 0.768** | 0.609** | 0.730** | - | -0.291 | |
HPF | 0.692** | 0.513** | 0.613** | - | -0.175 | ||
Vitamin D 24 weeks | CTX | 0.919** | 0.565 | 0.884** | - | -0.106 | |
HPF | 0.679* | 0.715* | 0.765** | - | 0.006 | ||
Rats | PTX 12 weeks | CTX | - | -0.458 | -0.605 | -0.608* | 0.475 |
HPF | - | -0.722* | -0.502 | -0.079 | 0.726* | ||
PTX 24 weeks | CTX | - | -0.366 | -0.629* | -0.228 | 0.482 | |
HPF | - | -0.674* | -0.099 | -0.48 | 0.325 | ||
Rats | PTH Infusion 6 weeks | CTX | - | -0.182 | -0.573 | - | 0.001 |
HPF | - | -0.051 | 0.401 | - | -0.02 | ||
PTH Infusion 12 weeks | CTX | - | -0.212 | -0.127 | - | -0.228 | |
HPF | - | 0.208 | 0.014 | - | 0.026 |
Correlation coefficients of cerebral capillary permeability (IgG) in both cerebral cortex (CTX) and hippocampal formation (HPF) with vitamin D, blood ionised calcium, serum total calcium, parathyroid hormone and serum phosphate for all vitamin D supplemented experimental groups (rats and mice), parathyroid gland ablated (PTX) and parathyroid hormone-infused (PTH-infusion) groups are represented in this table. (**p<0.01; *p<0.05; n = 4–10; Pearson’s analysis).