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. 2015 Apr 13;10(4):e0122360. doi: 10.1371/journal.pone.0122360

Table 3. CA125/Gal-3 categories and risk of adverse events.

All-cause mortality
Adjusted HR (CI 95%), p-value Adjusted HR (CI 95%), p-value
Gal-3 >17.8 ng/ml and CA125 ≤67 U/ml 1 Gal-3 >22.3 ng/ml and CA125 ≤67 U/ml 1
Gal-3 >17.8 ng/ml and CA125 >67 U/ml 2.16 (1.29–3.64) p = 0.004 Gal-3 ≤22.3 ng/ml and CA125 >67 U/ml 1.91 (1.06–3.43) p = 0.032
Gal-3 ≤17.8 ng/ml and CA125 ≤67 U/ml 1.30 (0.66–2.53) p = 0.445 Gal-3 >22.3 ng/ml and CA125 ≤67 U/ml 0.79 (0.41–1.51) p = 0.478
Gal-3 ≤17.8 ng/ml and CA125 >67 U/ml 1.59 (0.84–3.01) p = 0.151 Gal-3 >22.3 ng/ml and CA125 >67 U/ml 1.46 (0.74–2.88) p = 0.272
Repeated hospitalizations
Adjusted IRR (CI 95%), p-value Adjusted IRR (CI 95%), p-value
Gal-3 >17.8 ng/ml and CA125 ≤67 U/ml 1 Gal-3 >22.3 ng/ml and CA125 ≤67 U/ml 1
Gal-3 >17.8 ng/ml and CA125 >67 U/ml 1.53 (1.07–2.19) p = 0.019 Gal-3 ≤22.3 ng/ml and CA125 >67 U/ml 1.42 (0.96–2.10) p = 0.077
Gal-3 ≤17.8 ng/ml and CA125 ≤67 U/ml 1.06 (0.64–1.76) p = 0.822 Gal-3 >22.3 ng/ml and CA125 ≤67 U/ml 0.96 (0.62–1.46) p = 0.838
Gal-3 ≤17.8 ng/ml and CA125 >67 U/ml 0.87 (0.57–1.34) p = 0.525 Gal-3 >22.3 ng/ml and CA125 >67 U/ml 1.07 (0.69–1.66) p = 0.768

CA125: carbohydrate antigen 125; Gal-3: galectin-3; HR; hazard ratio; IRR: incident rate ratio.