Table 3. CA125/Gal-3 categories and risk of adverse events.
All-cause mortality | |||
Adjusted HR (CI 95%), p-value | Adjusted HR (CI 95%), p-value | ||
Gal-3 >17.8 ng/ml and CA125 ≤67 U/ml | 1 | Gal-3 >22.3 ng/ml and CA125 ≤67 U/ml | 1 |
Gal-3 >17.8 ng/ml and CA125 >67 U/ml | 2.16 (1.29–3.64) p = 0.004 | Gal-3 ≤22.3 ng/ml and CA125 >67 U/ml | 1.91 (1.06–3.43) p = 0.032 |
Gal-3 ≤17.8 ng/ml and CA125 ≤67 U/ml | 1.30 (0.66–2.53) p = 0.445 | Gal-3 >22.3 ng/ml and CA125 ≤67 U/ml | 0.79 (0.41–1.51) p = 0.478 |
Gal-3 ≤17.8 ng/ml and CA125 >67 U/ml | 1.59 (0.84–3.01) p = 0.151 | Gal-3 >22.3 ng/ml and CA125 >67 U/ml | 1.46 (0.74–2.88) p = 0.272 |
Repeated hospitalizations | |||
Adjusted IRR (CI 95%), p-value | Adjusted IRR (CI 95%), p-value | ||
Gal-3 >17.8 ng/ml and CA125 ≤67 U/ml | 1 | Gal-3 >22.3 ng/ml and CA125 ≤67 U/ml | 1 |
Gal-3 >17.8 ng/ml and CA125 >67 U/ml | 1.53 (1.07–2.19) p = 0.019 | Gal-3 ≤22.3 ng/ml and CA125 >67 U/ml | 1.42 (0.96–2.10) p = 0.077 |
Gal-3 ≤17.8 ng/ml and CA125 ≤67 U/ml | 1.06 (0.64–1.76) p = 0.822 | Gal-3 >22.3 ng/ml and CA125 ≤67 U/ml | 0.96 (0.62–1.46) p = 0.838 |
Gal-3 ≤17.8 ng/ml and CA125 >67 U/ml | 0.87 (0.57–1.34) p = 0.525 | Gal-3 >22.3 ng/ml and CA125 >67 U/ml | 1.07 (0.69–1.66) p = 0.768 |
CA125: carbohydrate antigen 125; Gal-3: galectin-3; HR; hazard ratio; IRR: incident rate ratio.