Fig 6. Cu/Zn-SOD and Mn-SOD protein expressions.
WIN prevents Cu/Zn-SOD expression decrease in astrocytes in primary culture treated with Aβ1–42. Cu/Zn-SOD, Mn-SOD and α-tubulin expressions were determined by Western-blot in astrocytes treated for 24 h with 10 μM Aβ40–1 (control peptide, C), 10 μM Aβ1–42 (Aβ), 10 μM WIN + 10 μM control peptide (WIN) and 10 μM WIN + 10 μM Aβ1–42 (WIN + Aβ). A representative immunoblot of each protein is shown and tubulin was used as control amount of protein. Data are means ± SD of 4 independent experiments. *p<0.05 vs control cells. #p<0.05 vs Aβ1–42.