Table 3. Groupings for structure models based on envelope similarity. Protein Data Bank (PDB) and ligand identifiers match those used in Table 1.

Group #	PDB ID	Pharmacophore model ligand ID
1	1FM6, 1ZGY, 2PRG, 2VSR, 2VV2	BRL1, MYI1, 9HO3, HXA3
2	1FM9, 1K74, 1RDT, 2I4Z, 2POB	BRL1, MYI1, SF22, ZXG2
3	2I4J, 2VSR, 2VST, 2VV0, 2VV1, 2VV2	SF22, ZXG2, 9HO3, HXA3
4	2I4Z, 2P4Y, 2Q5P	SF22, ZXG2
5	2Q5S, 2Q6R	SF22, ZXG2
6	1WM0, 2FVJ, 2G0G, 2G0H, 2HFP, 2I4P, 2OM9, 2Q6S, 3B3K, 3CDP, 3CS8, 3DZU, 3DZY, 3E00, 4PRG

Activity type indicated by the following:

¹full agonist,

²partial agonist,

³fatty acid